Computer Simulations of Protein Folding
نویسندگان
چکیده
Computer simulation holds great promise to significantly complement experiment as a tool for biological and biophysical characterization. Simulations offer the promise of atomic spatial detail with femtosecond temporal resolution. However, the application of computational methodology has been greatly limited due to fundamental computational challenges: put simply, for much of what one would want to examine, atomistic simulations would require decades to millennia to complete. Below, we detail current methods to tackle these challenges as well as recent applications of this methodology.
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